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We thank Prof. Peng Zhou (Wuhan, China) for kindly providing materials and thank Yan Wu and Weijuan Shang for experimental assistance. This work was supported by the Strategic Priority Research Progra...
The gastrointestinal epithelium is covered by a protective mucus gel composed predominantly of mucin glycoproteins that are synthesized and secreted by goblet cells. Changes in goblet cell function...
Flavonoids may exert their health benefit in cardiovascular disease by modulating monocyte adhesion in the inflammatory process of atherosclerosis. Most in vitro studies used forms of flavonoids pr...
Polyphenolic phytochemicals inhibit vascular and inflammatory processes that contribute to disease. These effects are hypothesized to result from polyphenol-mediated alterations in cellular eicosan...
A recent task force of The American Society for Clinical Nutrition and American Society for Nutritional Sciences recommended in a position paper on trans fatty acids that models be developed to ass...
Lycopene has been identified as a phytochemical with potentially protective health benefits.
The potential benefits of increasing calcium intake in small children must be balanced with the potential risk to iron utilization from high calcium intakes.
Breast cancer is one of the leading causes of death in women cancer cases worldwide. Cancer is the result of environmental and genetic factors that contribute to alterations in cellular control, proli...
In a first-of-its-kind experiment, the unique conditions of space flight will be used to examine how cells remain healthy or succumb to disease, particularly in the face of stress or damage.
BSA antigen sensitization during the acute phase of influenza A viral infection enhanced IL-10 production from naïve CD4+ T cell interaction with CD11c+ pulmonary APCs. The IL-10 secretion evoked...
Background:Atherosclerosis is a chronic inflammatory disease. We previously reported that a diet high in -linolenic acid (ALA) reduces lipid and inflammatory cardiovascular disease risk factors in hyp...
The aim of this study was to determine the effects of vitamin E (α-tocopherol) on the low density lipoprotein (LDL) receptor, a cell surface protein which plays an important role in controlling blood ...
The nucleoside analogue arabinosylcytosine (araC) has been used for many years in the treatment of acute leukemia. Evidence in the literature suggests that araC may inhibit the growth of human colon c...
Background High fruit and vegetable intake is known to reduce the risk of colon cancer. To improve understanding of this phenomenon the action of different phytochemicals on colon cells has been exam...
期刊信息 篇名 (2)α,α-Trehalose derivatives bearing guanidine groups as inhibitors to HIV-1 Tat-TAR RNA interaction in human cells. 语种 英文 撰写或编译 作者 王敏,杨铭 第一作者单位 刊物名称 Bioorganic & Medicinal Chemistry Letters 页...

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