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Background: Reduced potassium excretion caused by angiotensin-converting enzyme inhibitors (ACEis) and angiotensin receptor blockers (ARBs) may increase the risk of hyperkalemia (serum potassium conce...
Over the last two decades, there has been an impressive growth of experimental and clinical evidence defining a role for the renin-angiotensin system (RAS) in the development of ischemic cardiovascul...
Angiotensin I-converting Enzyme (ACE) gene polymorphism; genotype DD or D allele may be involved with an increased susceptibility to type 2 diabetes and diabetic nephropathy (DN). We examined the freq...
Renin angiotensin system (RAS) has an important role in the regulation of hypertension. RAS includes angiotensinogen, Angiotensin Converting Enzyme (ACE), angiotensine II and angiotensin receptors (AG...
Every year the FDA approves approximately 25 new chemical entities (NCE) which are subsequently marketed and introduced into medical and pharmaceutical practice. Many of these new compounds, such as c...

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