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Determination of the Intrinsic Efficacies of β2 -adrenergic Agonists
efficacy epinephrine fenoterol procaterol β2-adrenergic agonist
2010/11/19
β-adrenergic agonists have been traditionally classified as strong or weak. Attempts to express their effectiveness in quantitative terms has led to the concepts of potency, which designates the conce...
In vitro Comparison of the Intrinsic Activity of Functional Antagonism between β-agonists and Spasmogens in the Guinea-pig Tracheal Muscle
carbachol contraction functional antagonism guinea-pig trachea intrinsic activity potency β-agonists
2010/11/19
Relaxation responses to β-agonists were diminished depending on the extent of carbachol-induced tone in the tracheal muscle. The degree of hyporesponsiveness was greatest in treatment with tulobuterol...