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Intratumour heterogeneity in the progression to breast cancer metastasis
Intratumour heterogeneity breast cancer metastasis
2015/4/14
Unlike the great advances that have been made in reducing breast cancer mortality through the multidisciplinary treatment of primary disease, much less is understood about the natural history of metas...
Bisphosphonate Treatment Modifies Canine Bone Mineral and Matrix Properties and their Heterogeneity
bisphosphonates bone remodeling
2014/12/4
Bone loss and alterations in bone quality are major causes leading to bone fragility in postmenopausal women. Although bisphosphonates are well known to reduce bone turnover and prevent bone loss in p...
Heterogeneity of 3’-Untraslated Region of Genome RNA of the Tick-Borne Encephalitis Virus (TBEV) Strains Isolated from Ticks in the Western Siberia, Russia
deletions hemagglutination neurovirulence reverse transcription–polymerase chain reaction
2009/4/20
The tick-borne encephalitis virus (TBEV) strains have been isolated from unfed adult ticks Ixodes persulcatus Schulze in Novosibirsk region (South-Western Siberia, Russia) beginning from 1980 till 200...
Heterogeneity of sperm density profiles following 16-week therapy with continuous infusion of high-dose LHRH analog plus testosterone
sperm density profiles 16-week therapy high-dose LHRH testosterone
2009/2/23
LHRH agonist analogs have been investigated as potential male contraceptives. It has been shown that the LHRH agonistic analog [D-Trp6,Pro9-NEt] LHRH (LHRHA) given to men in single doses up to 500 m...
The heterogeneity of rat androgen binding protein（rABP）in the vascular compartment differs from that in the testicular tubular lumen. Further evidence for bidirectional secretion of rABP
rat ABP ABP heterogeneity
2009/2/23
Fractionation of testicular extracts and serum on a Concanavalin A-Sepharose column resolved two peaks of immunoreactive rat androgen binding protein. The rat androgen binding protein in the first pea...
Heterogeneity of sperm density profiles following 20-week therapy with high-dose LHRH analog plus testosterone
LHRH analog sperm density heterogeneous response
2009/2/20
Eight normal male volunteers received an LHRH analog, 100 to 500 micrograms daily, for 20 weeks. Testosterone enanthate, 100 mg, was given by injection every second week. Sperm density fell to 5.5 X...
Improvement of cryopreserved ram sperm heterogeneity and viability by addition of seminal plasma
cryopreserved ram sperm heterogeneity seminal plasma
2009/2/17
The effect of seminal plasma, as well as some seminal plasma fractions, on the heterogeneity and viability of frozen-thawed ram spermatozoa was studied. Fresh and frozen sperm samples were simulta...
Heterogeneity of gonadotropins and levels of uncombined luteinizing hormone subunits in pituitaries of cryptorchid rams
uncombined luteinizing hormone subunits pituitaries cryptorchid rams
2009/2/12
Pituitaries were collected from intact rams and rams that had been rendered bilaterally cryptorchid by surgery to examine the effects of cryptorchidism on gonadotropin heterogeneity, levels of uncom...
Heterogeneity of adult mouse Leydig cells with different buoyant densities
Heterogeneity adult mouse Leydig cells different buoyant densities
2009/2/10
The authors investigated the morphologic characteristics and human chorionic gonadotrophin (hCG)-stimulated testosterone production of adult mouse Leydig cells in vitro, which have different buoya...
Heterogeneity in Vertical Positioning of the Hyoid Bone in Relation to Genioglossal Activity in Men
Cephalometrics Genioglossus muscle Hyoid bone OSA
2008/12/11
The aim of this study was to investigate whether there is any relationship among genioglossus (GG) baseline electromyographic (EMG) activity, upper airway resistance, and sex. We hypothesized that GG ...
Heterogeneity of bronchial response to exercise among children with asthma
asthma children exercise-induced broncho-obstruction types of response
2010/11/25
The test resulted in four types of response to exercise: (i) non-obstructive; (ii) isolated early airway response (EAR); (iii) dual-waved; and (iv) prolonged EAR. The frequency of these responses in t...