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Coenzyme Q10 prevents hepatic fibrosis, inflammation, and oxidative stress in a male rat model of poor maternal nutrition and accelerated postnatal growth
developmental programming liver disease coenzyme Q low birth weight accelerated postnatal growth
2018/11/28
Background: It is well established that low birth weight and accelerated postnatal growth increase the risk of liver dysfunction in later life. However, molecular mechanisms underlying such developmen...
Vagal modulation of intestinal afferent sensitivity to systemic LPS in the rat
autonomic innervation electrophysiology mesenteric vagus nerve visceral hypersensitivity lipopolysaccharide
2014/5/16
Liu CY, Mueller MH, Grundy D, Kreis ME. Vagal modulation of intestinal afferent sensitivity to systemic LPS in the rat. Am J Physiol Gastrointest Liver Physiol 292: G1213–G1220, 2007. First published ...
Four-vessel occlusion model,Both vertebral arteries are cauterized,Both common carotid arteries are clamped,Duration of ischemia: 15–30 min.
T he relative order of mK channels, free radicals and p38 MAPK in ATP preconditioning’s protective pathway in rat heart
Free radicals Infarction Ischemia Mitochondria Preconditioning Signal transduction
2014/3/31
Ischemic preconditioning (PC) reduces myocardial infarction by a mechanism that involves opening of mitochondrial
ATP-dependent potassium channels (mK ), reactive oxygen species (ROS), and possibly a...
Induction of Tolerance to Focal Ischemia in Rat Brain: Dissociation Between Cortical Lesioning and Spreading Depression
Rat Brain Cortical Lesioning Spreading Depression
2014/3/31
Cortical application of KCl has previously been
shown to induce tolerance to a subsequent episode of cerebral
ischemia. KCl triggers recurrent episodes of cortical spreading
depression and produces...
Vascular effects of caffeic acid phenethyl ester (CAPE) on isolated rat thoracic aorta
CAPE Thoracic aorta Vasorelaxation Phenylephrine Contraction Calcium
2014/3/31
This study was aim ed to inves tigate the vascular activity of caffeic acid phenethyles ter (CAPE), one of the
major compo nents of honeybee p ropolis. Exp eriments were performed o n rat thora cic a...
Role of membrane potential in vasomotion of isolated pressurized rat arteries
Vasomotion Electrical oscillation Norepinephrine Intracellular calcium Electrophysiology Smooth muscle
2014/3/31
Vasom otion, the phenom enon of vessel diam eter oscil lation, regul ates blood flow and resi stance. The main
param eters implic ated in vasom otion are particula rly the mem brane potent ial and th...