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LymphTF Database- A Database of Transcription Factor Activity in Lymphocyte Development
lymphocyte development LymphTF Database DNA bioinformatics
2015/1/9
Study of the transcriptional regulation of lymphocyte development has advanced greatly in the past 15 years. Owing to improved techniques and intense interest in the topic, a great many interactions b...
Twist1 and Etv5 are part of a transcription factor network defining T helper cell identity
Twist1 Etv5
2015/5/21
CD4 T helper cells control immunity to pathogens and the development of inflammatory disease by acquiring the ability to secrete effector cytokines. Cytokine responsiveness is a critical component of ...
耦联性转录与翻译新进展:真核生物细胞核内的翻译The New Advance of Coupled Transcription and Translation:Translation within the Nuclei in Eukaryotes
耦联性转录与翻译 细胞核 生物素
2007/12/7
摘要原核生物转录与翻译过程是耦联的。通常认为，在真核生物中，初级转录产物经过加工和修饰成的mRNA从细胞核进入细胞质后，翻译才开始，也就是说，转录与翻译过程并不是耦联的。然而，最近Iborra 等人用赖氨酸［3H］以及生物素或BODIPY标记的赖氨酸-tRNA对哺乳动物细胞翻译位点进行定位，发现细胞核内存在耦联性转录与翻译过程，核内翻译产物占细胞总合成蛋白的10%~15%。
Abstract:I...