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近日,内蒙古大学生命科学学院包斯琴教授、李喜和教授与北京大学汤富酬教授团队合作在Science China Life Sciences(《中国科学:生命科学》英文版)发表题为“Blastoids generated purely from embryonic stem cells both in mice and humans”的文章。该工作开发了一种在化学成分明确的培养条件中,使用一步法加单因子...
作为细胞代谢网络的中心,线粒体的功能与衰老以及神经退行性疾病和癌症等疾病密切相关。当线粒体受到胁迫时,细胞会自主激活胁迫响应来维持线粒体内稳态,值得注意的是,在没有遭受胁迫的组织或细胞中,线粒体胁迫响应也可以通过一种非自主的方式被激活,这种非自主线粒体胁迫响应是由一类称为mitokine的分泌因子介导的。由于其在改善人类代谢健康方面的潜力,科学家们围绕mitokine展开了大量的研究。
线粒体是细胞中重要的能量供应场所和代谢中心,主要通过氧化磷酸化过程合成ATP为细胞提供能量。线粒体同时也参与调控先天性免疫及细胞程序性死亡等生理过程。线粒体功能损伤会影响细胞甚至机体的正常生命活动,诱发一系列严重疾病例如神经功能障碍,慢性病,心力衰竭等,因此保障线粒体正常运作(内环境稳态)具有重要意义。而线粒体未折叠蛋白质反应(mitochondrial unfolded protein resp...
We are pleased to announce the Cold Spring Harbor Asia conference on Iron, Reactive Oxygen Species & Ferroptosis in Life, Death & Disease which will be held in Suzhou, China, located approximately 60 ...
The study of the origin of life occurs at an intersection of chemistry, physics, biology, geology, astronomy, and other fields. Conversations between these fields yield new insight and correct biases ...
We are pleased to announce the Cold Spring Harbor Asia conference on Iron, Reactive Oxygen Species & Ferroptosis in Life, Death & Disease which will be held in Suzhou, China, located approximately 60 ...
The Anthropocene is recognized (though not yet formally defined) as the time when human impacts are widespread on Earth. While some of the impacts are essential to supporting large human populatio...
Viruses have evolved to exploit cellular pathways and machinery in order to deliver their genome to the cell, replicate, and produce viral progeny. Nonenveloped viruses must overcome membrane barriers...
A new technique that allows researchers to conduct experiments more rapidly and accurately is giving insights into the workings of proteins important in heart and muscle diseases.
Life on the edge: morphological and behavioral adaptations for survival on wave-swept shores。

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