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New prediction algorithm identifies previously undetected cancer driver genes（图）
New prediction algorithm identifies previously undetected cancer driver genes
2020/12/11
A new study, led by U.S. National Science Foundation-funded researchers at the University of California, Irvine, has deepened the understanding of epigenetic mechanisms in tumorigenesis and ...
Measuring the health of the Chesapeake Bay: toward integration and prediction
health of the Chesapeake Bay integration prediction
2016/5/19
Measuring the health of the Chesapeake Bay: toward integration and prediction.
Class prediction by nearest shrunken centroids,with applications to DNA microarrays.
Class prediction nearest shrunken centroids DNA microarrays
2015/8/21
Class prediction by nearest shrunken centroids,with applications to DNA microarrays..
In Silico Target Prediction by Training Naive Bayesian Models on Chemogenomics Databases
Chemogenomics Databases Informatics
2015/5/26
The completion of Human Genome Project is seen as a gateway to the discovery of novel drug targets (Jacoby, Schuffenhauer, & Floersheim, 2003). How much of this information is actually translated into...
Protein function prediction by integrating sequence, structure and binding affinity information
protein function binding affinity information
2015/5/26
Proteins are nano-machines that work inside every living organism. Functional disruption of one or several proteins is the cause for many diseases. However, the functions for most proteins are yet to ...
Prediction by Partial Matching for Identification of Biological Entities
Identification Partial Matching Prediction
2015/5/26
As biomedical research and advances in biotechnology generate expansive datasets, the need to process this data into information has grown simultaneously. Specifically, recognizing and extracting thes...
USE OF APRIORI KNOWLEDGE ON DYNAMIC BAYESIAN MODELS IN TIME-COURSE EXPRESSION DATA PREDICTION
DYNAMIC BAYESIAN NETWORKS HIDDEN MARKOV MODELS
2015/5/26
Bayesian networks, one of the most widely used techniques to understand or predict the future by making use of current or previous data, have gained credence over the last decade for their ability to ...
Optimizing hydropathy scale to improve IDP prediction and characterizing IDPs' functions
Intrinsically disordered proteins Support vector machine Clustering
2015/5/25
Intrinsically disordered proteins (IDPs) are flexible proteins without defined 3D structures. Studies show that IDPs are abundant in nature and actively involved in numerous biological processes. Two ...
Prediction of Eggshell Ultrastructure via Some Non-destructive and Destructive Measurements in Fayoumi Breed
Non-destructive and Destructive Measurements Prediction Equations Fayoumi Breed
2016/5/18
Possibilities of predicting eggshell ultrastructure from direct non-destructive and destructive measurements were examined using 120 Fayoumi eggs collected from the flock at 45 weeks of age. The non-d...
Determination and Prediction of the Amino Acid Digestibility of Sunflower Seed Meals in Growing Pigs
Chemical Composition Amino Acid Digestibility Growing Pigs Prediction Equations
2016/5/17
This experiment was conducted to evaluate the chemical composition and amino acid (AA) digestibility of sunflower seed meal (SFSM) and to use this data to develop prediction equations for estimating A...
Evaluation of the IrisPlex DNA-based eye color prediction tool in the United States
DNA forensic biology genotype data single nucleotide polymorphisms unknown biological samples the scene of the crime
2015/5/22
DNA phenotyping is a rapidly developing area of research in forensic biology. Externally visible characteristics (EVCs) can be determined based on genotype data, specifically from single nucleotide po...
Identification and Function Prediction of Novel MicroRNAs in Laoshan Dairy Goats
MicroRNA Mammary Gland Goat Solexa High-throughput Sequencing
2016/5/11
MicroRNAs are a class of endogenous small RNAs that play important roles in post-transcriptional gene regulation by directing degradation of mRNAs or facilitating repression of target gene translation...
Accurate prediction of gene expression by integration of DNA sequence statistics with detailed modeling of transcription regulation
gene expression DNA sequence statistics detailed modeling transcription regulation
2011/1/5
Gene regulation involves a hierarchy of events that extend from specific protein-DNA interactions to the combinatorial assembly of nucleoprotein complexes. The effects of DNA sequence on these process...
Epidemic prediction and control in clustered populations
Epidemic prediction control clustered populations
2011/1/5
There has been much recent interest in modelling epidemics on networks, particularly in the presence of substantial clustering. Here, we develop pairwise methods to answer questions that are often add...
Rapid and Accurate Protein Side Chain Prediction with Local Backbone Information
side chain prediction local backbone features multiclass
2012/11/30
High-accuracy protein structure modeling demands accurate and very fast side chain prediction since such a procedure must be repeatedly called at each step of structure refinement. Many known side cha...