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第二次药物发现转运体研讨会（The 2nd Symposium on Transporters in Drug Discovery）
structural biology Drug Discovery
2017/1/19
Cell surface transporters play a key role in human health and disease, both through their impact on drug disposition and as therapeutic targets in their own right. This meeting continues on from the...
《Transporters in Drug Development: Discovery, Optimization, Clinical Study and Regulation》（图）
Transporters in Drug Development: Discovery, Optimization, Clinical Study and Regulation Yuichi Sugiyama Bente Steffansen
2013/12/4
With chapters written by leading researchers in the transporter field from academia, pharmaceutical industry, and regulatory agencies, this volume advises on how membrane transporters can be dealt wit...
Histochemical demonstration of monocarboxylate transporters in mouse brown adipose tissue
Histochemical demonstration monocarboxylate transporters
2009/12/16
Proton-coupled monocarboxylate transporters (MCTs) are essential for the transport of lactate, ketone bodies, and other monocarboxylates through the plasma membrane. The present immunohistochemical st...
Drug-Metabolizing Enzymes and Transporters：Expression in the Human Prostate and Roles in Prostate Drug Disposition
Drug-Metabolizing Enzymes Transporters Human Prostate Prostate Drug Disposition
2008/12/23
Local biotransformation enzymes and transporter proteins in tissues may exert a profound effect on drug pharmacokinetics in those tissues. Thus, the use of drugs for the treatment of benign prostatic ...
Zinc and Metallothionein Levels and Expression of Zinc Transporters in Androgen-Independent Subline of LNCaP Cells
Hormone-refractory metallothionein ZnT1 ZnT3
2008/12/22
Zinc levels in the prostate have been reported to be associated with the development and progression of malignant prostate cells. To investigate the reason why the zinc content decreases during th...
Identification of Glutamate Receptors and Transporters in Mouse and Human Sperm
Uptake immunocytochemistry RT-PCR inhibitor
2008/12/22
-Aminobutyric acid (GABA) and glutamate (Glu) are considered as the predominant inhibitory and excitatory neurotransmitters in mammalian central nervous systems (CNS), respectively. The presence o...
Iron supplementation during infancy—effects on expression of iron transporters, iron absorption, and iron utilization in rat pups
Rat pups infants divalent metal transporter 1
2017/1/5
Studies conducted in human infants suggest developmental changes in the regulation of iron absorption; however, little is known about the molecular mechanisms regulating iron absorption during infancy...