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Comparison of Metformin and Simvastatin Administration in Women With Polycystic Ovary Syndrome Before Intra-Cytoplasmic Sperm Injection Cycle: A Prospective, Randomized, Clinical Trial Study
Metformin Simvastatin Polycystic Ovary Syndrome Intracytoplasmic Sperm Injection
2015/12/29
Background: Drugs administration as a pretreatment regiment before ICSI cycle in PCOs patients could enhance the success rate.
Effects of Simvastatin Treatment on Serum Adiponectin Concentrations in Patients With Dislipidemia
Atherosclerosis Adiponectin Statins
2015/10/14
Background: Adiponectin is an adipose tissue-derived protein with anti-inflammatory properties. Statins are a class of cholesterol-lowering drugs, widely used for treatment of cardiovascular diseases.
The influence of ovariectomy,simvastatin and sodium alendronate on alveolar bone in rats
Alendronate Models animal Osteoporosis Ovariectomy Simvastatin
2009/10/19
Bisphosphonates are currently used in the treatment of many diseases involving increased bone resorption such as osteoporosis. Statins have been widely used for the treatment of hypercholesterolemia a...
Controlled Release of Simvastatin Acid Using Cyclodextrin Inclusion System
Simvastatin acid Cyclodextrin derivative Controlled drug release
2009/9/14
Simvastatin acid (SVA) has been reported to stimulate bone formation by increasing expression of BMP-2 in osteoblasts. Due to their multi-functional characteristics and bioadaptability, cyclodextrins ...
The Effect of Simvastatin Treatment on Plasma Ubiquinone,Blood ATP Concentrations, Total Antioxidant Capacity and Muscle Related Markers
Ubiquinone HMG CoA reductase inhibitors ATP antioxidant
2009/6/26
It has been hypothesized that treating hypercholesterolemic patients with statins will lead not only to a reduction in cholesterol, but also to inhibited synthesis of other compounds that derive from ...
Induction of TGF-β and BMP-2 by Simvastatin in Human Periodontal Ligament Cells
simvastatin human periodontal ligament (HPDL) cells transforming growth factor-β1 (TGF-β1) bone morphogenetic protein-2 (BMP-2)
2009/5/21
Statins, which are highly effective cholesterol-lowering drugs, induce bone morphogenetic protein (BMP)-2 expression. However, the other growth factors except for BMP-2 and the effects of statins on p...
Simvastatin inhibits tissue factor and plasminogen activator inhibitor-1 expression of glomerular mesangial cells in hypercholesterolemic rabbits
Simvastatin inhibits tissue factor plasminogen activator inhibitor-1 glomerular mesangial cells
2009/3/2
Tissue factor (TF) and plasminogen activator inhibitor-1 (PAI-1) activity and/or expression are upregulated in hypercholesterolemia. Despite extensive research on anti-thrombotic effect of statins, ...
Oxygen plasma surface modification enhances immobilization of simvastatin acid
Oxygen plasma surface modification immobilization simvastatin acid
2009/3/2
Simvastatin acid (SVA) has been reported to stimulate bone formation with increased expression of BMP-2. Therefore, immobilization of SVA onto dental implants is expected to promote osteogenesis at ...
Does TGF beta suppressing effect of simvastatin lead to protection against surgical adhesion band formation?
Simvastatin Intra abdominal adhesion bands Bowel obstruction Transforming growth factor beta
2010/5/7
Intra-abdominal adhesions are the most common cause of small bowel obstruction. Infertility in women and chronic abdominal-pelvic pain are the other problems of adhesiogenesis which impose a great eco...
Does TGF beta suppressing effect of simvastatin lead to protection against
Simvastatin Intra abdominal adhesion bands Bowel obstruction Transforming growth factor beta
2010/5/7
Intra-abdominal adhesions are the most common cause of small bowel obstruction. Infertility in women and chronic abdominal-pelvic pain are the other problems of adhesiogenesis which impose a great eco...