搜索结果: 1-9 共查到“多肽与蛋白质生物化学 Research”相关记录9条 . 查询时间(0.125 秒)
近日，应“核酸研究”高级执行主编Julian Sale的邀请，中南大学湘雅医院国家卫健委肿瘤蛋白质组学重点实验室陈永恒教授团队在国际权威学术期刊Nucleic Acids Research（IF=16.97）上发表题为“Toward a mechanistic understanding of DNA binding by forkhead transcription factors and it...
浙江大学医学院段树民院士团队Cell Research发文报道溶酶体蛋白酶cathepsin D具有pH及构象依赖的双重酶活性（图）
浙江大学医学院 段树民院士 Cell Research 溶酶体蛋白酶 cathepsin D pH 构象依赖 双重酶活性
2021/2/4
溶酶体中存在多种负责降解多肽或蛋白质的蛋白水解酶。为确保它们在特定部位与环境发挥催化作用、避免“滥杀无辜”，蛋白水解酶通常以酶原的形式在囊泡内大量储存。在传统认识中，酶原是不具有催化活性的前体蛋白。然而，酶原在功能上真的只是“沉默的大多数”吗？
中国科学院昆明动物研究所赖仞课题组牵头以封面文章在Circulation Research发表缺铁性贫血和口服避孕药诱导脑卒中分子机制（图）
赖仞 缺铁性 贫血 口服避孕药 脑卒中 分子机制
2020/8/17
中国科学院昆明动物研究所赖仞研究员领导的团队最近发现缺铁和雌激素分别通过调控转铁蛋白基因调控区的低氧诱导元件（HRE）和雌激素反应元件（ERE）从而上调转铁蛋白的表达，这表明转铁蛋白上调与缺铁性贫血和口服避孕药的使用之间存在关联。前期研究已经阐明血浆转铁蛋白与凝血因子和抗凝血因子以不同的亲和力相互作用以维持凝血系统稳态平衡（Tang et al. Cell research. 2020）。进一步的...
2017 “健康和疾病翻译机”高登研究研讨会（The Gordon Research Seminar on Translation Machinery in Health and Disease）
Health Disease
2017/3/8
The Gordon Research Seminar on Translation Machinery in Health and Disease is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education t...
The Gordon Research Seminar on Proteins is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and...
The 2017 Proteins Gordon Research Conference has been conceived with two underlying leitmotifs. The first is to highlight proteins as cellular organizers, while the second and equally central theme of...
2017应激蛋白在生长，发育和疾病戈登学术会议（The 2017 Gordon Research Conference on Stress Proteins in Growth, Development & Disease）
Stress Proteins Growth Development Disease
2017/1/18
The cellular proteome is constantly exposed to a wide variety of proteotoxic stress conditions. These include external stresses, such as elevated temperatures and radiation damage as well as physiolog...
2017弹性蛋白，弹性纤维和微纤维戈登学术会议（The 2017 Gordon Research Conference on Elastin, Elastic Fibers & Microfibrils）
Elastic Fibers Microfibrils
2017/1/18
Elastin, fibrillin microfibrils and an array of associated proteins form elastic fibers which are critical for the formation of the skin, vasculature, lungs, bones, tendons, eyes and other tissues. Ad...
2017"Posttranslational Modification Networks"戈登学术会议（The 2017 Gordon Research Conference on Posttranslational Modification Networks）
genomics proteomics mass spectrometry
2017/1/18
The 2017 Gordon Conference on Posttranslational Modification Networks will present the latest development on approaches how the protein machinery and signaling pathways function in the context of vari...